This is the perfect opportunity for Parris Campbell to step up. Coach Frank Reich said this week that Campbell has progressed so much that the Colts can line him up anywhere on the field -- in the slot, out wide or use him in motion. None of that will mean anything if Campbell can't stay healthy. He has played only nine games in his first two seasons because of injuries. -- Mike Wells
Marvin Jones Jr. has been Trevor Lawrence's favorite target throughout training camp. Lawrence targeted Jones nine times when they were on the field with the first-team offense in the first two preseason games. So expect Lawrence to continue to look for Jones a lot, especially when it's a key situation or he is scrambling. -- Michael DiRocco
Jones should be heavily involved in the game plan this week. It's like getting a new car and taking it out for a spin to show it off. Expect the Titans to make it a point to display how Jones and Ryan Tannehill can be a productive tandem, especially against the Cardinals' cornerbacks. -- Turron Davenport
One thing Bridgewater has shown throughout his training camp battle to win the starting job as well as his work in three preseason games -- 73.3% completions, three TDs, no interceptions with just one possession he was behind center in which the team did not score points -- is his willingness to move the ball around to where the defense wasn't. So the "go-to'' tag could move around this season. But Courtland Sutton has waited since suffering a knee injury in Week 2 in 2020 to get back on the field. And in the only preseason game Sutton played last month, he and Bridgewater showed a quick affinity, including a touchdown. -- Jeff Legwold
Kansas City Chiefs
Will the preseason usage of Mecole Hardman result in improved regular-season numbers starting on Sunday?
As long as Tyreek Hill and Travis Kelce are in the lineup, it's difficult to see any other Chiefs receiver getting the ball on a consistent basis. Hardman will have his big games, but with Patrick Mahomes having so many other receivers to feed, they won't happen every week. -- Adam Teicher
Las Vegas Raiders
Is there a pass-catcher not named Darren Waller who will see consistent volume?
Yes, or have you forgotten about Derek Carr's security blanket, the guy who goes by the nickname "Third-and-Renfrow"? Now, Hunter Renfrow is never going to light up the stat sheet -- he has 105 catches for 1,261 yards and 6 TDs in two seasons -- but he is consistent. And while the Raiders have big plans for speedster Henry Ruggs III, Carr needs time for those downfield plays to develop and the offensive line is still a work in progress. Renfrow's intermediate routes provide production. -- Paul Gutierrez
Los Angeles Chargers
Who will rank fourth in targets behind Keenan Allen, Mike Williams and Austin Ekeler?
Rookie third-round pick Joshua Palmer had an amazing training camp. He was featured a lot in the preseason and will be a factor early, especially if injuries hit the Chargers' skill players. -- Shelley Smith
NFC EAST
Dallas Cowboys
Was the pass-heavy offensive attack on Thursday night -- 58 throws from Dak Prescott -- a sign of things to come or dictated by matchup?
Dictated by the matchup and who wasn't playing for the Cowboys: six-time Pro Bowl right guard Zack Martin. Ultimately, throwing that much isn't the recipe the Cowboys want. Prescott is now 4-11 in games in which he throws 40 or more passes. The Cowboys want to get running back Ezekiel Elliott involved more and have him be a central piece to the game plan, but they also don't want to be so stubborn that they just run into a brick wall over and over again. Tampa Bay lost a starting corner on the second drive and the Cowboys felt the best way to attack was with Prescott's arm. After the game, Prescott said the Cowboys will have games they have to lean on him and times they will lean on Elliott. -- Todd Archer
New York Giants
Over or under 17.5 touches for Saquon Barkley?
Under. That's a high number considering the way the Giants have handled the Barkley situation since the start. Joe Judge has been adamant about taking a long-range view with their star running back and mentioned Wednesday he can't possibly stress that enough. The Giants also have to be cognizant of playing two games in four days. A range of 10 to 15 touches seems more likely. -- Jordan Raanan
Philadelphia Eagles
Should we be comfortable in starting Jalen Hurts after an offseason of knowing he is "the guy"?
Yes. He was the ninth-best fantasy quarterback over the final four games of his rookie season despite playing behind an injury-ravaged offensive line and for an organization that was in full meltdown mode. The offensive front is healthier, the Eagles added reigning Heisman Trophy winner DeVonta Smith and coach Nick Sirianni's offense has been tailored to fit Hurts' skill set. Given that he can attack a defense with his arm and his legs, expect plenty of production. -- Tim McManus
Washington Football Team
What role do you expect Dyami Brown to play in his NFL debut?
With Curtis Samuel being placed on the IR on Friday with an ailing groin, it'll be larger than expected. They love Brown's speed, but they also say he is fearless on slants or going over the middle and he can be used on bubble routes. The big question, though, is how many targets he'll receive because there's a list of players I'd anticipate being ahead of him in opportunities -- Terry McLaurin, Adam Humphries, Logan Thomas and J.D. McKissic. Ryan Fitzpatrick also really likes Cam Sims, though Brown could take reps away from him. Still, I would expect them to use Brown's speed, not just on deep balls but on slants where he could break a long gain. -- John Keim
NFC NORTH
Chicago Bears
Who ranks second on this team in targets on Sunday night (and for the season)?
Second-year wide receiver Darnell Mooney. As a rookie last season, Mooney caught 61 passes for 631 yards and four touchdowns. Mooney is determined to top those numbers in Year 2. After Allen Robinson II, Mooney figures to be the most reliable target for Andy Dalton, and then for Justin Fields, whenever the rookie takes over. -- Jeff Dickerson
Detroit Lions
What will the touch split look like between D'Andre Swift and Jamaal Williams?
It's no secret that D'Andre Swift is expected to be the guy for Detroit at running back, with Jamaal Williams set to thrive as the No. 2 back in a strong complementary role. Throughout training camp, Swift was hampered with a groin injury that kept him out of preseason action and many practices, but he has been a full participant in practice this week and should see the bulk of the touches during the season opener as he is moving with no limitations. "I'm very bad at counting reps," said Lions running backs coach Duce Staley. "If he's out there being productive, 'What number is it Duce? Three.' It could be play 49, I don't know how to take him off." -- Eric Woodyard
Green Bay Packers
Will Robert Tonyan see more targets following an impressive 2020?
A strong case could be made that Tonyan is Aaron Rodgers' second-favorite target. And why not, considering he never drops the ball (OK, he dropped one once). Marquez Valdes-Scantling and Aaron Jones had slightly more targets than Tonyan did last season. All of them were way behind Davante Adams, but if teams put even more effort into slowing down Adams, Tonyan could certainly benefit. But after catching 11 TDs last season, Tonyan won't take anyone by surprise this year. -- Rob Demovsky
Minnesota Vikings
Can fantasy managers count on a tight end in this offense with Irv Smith Jr. out?
It's too early to tell if Tyler Conklin can pick up where Smith left off or if Chris Herndon finally replicates the success we saw him have in 2018 now that he is in a new offense. Mike Zimmer said the Vikings might have to go three wide more often with Smith likely sidelined for the year, and I'd expect a lot of those targets to go to Dede Westbrook, assuming he can stay healthy and emerge as WR3. The Vikings love running the ball and will probably rely on their tight ends to do more blocking than pass-catching early on. -- Courtney Cronin
NFC SOUTH
Atlanta Falcons
Can Mike Davis repeat his near 5 targets per game from 2020 with Carolina?
Probably not, and there are reasons for that. First would be overall target share -- Davis is likely fourth or fifth in line for targets (and that might be high) -- certainly behind Calvin Ridley and likely Russell Gage and Kyle Pitts, too. Combine that with his expanded role in the run game and the likely usage of Cordarrelle Patterson in passing situations for his receiving skills and five a game might be a bit much. Now, if he ends up as the Vikings' two-minute back in certain situations, that's where he could eclipse it, but don't expect that from week to week. -- Michael Rothstein
Carolina Panthers
Who is most likely to improve upon his 2020: DJ Moore or Robby Anderson?
Moore, particularly when it comes to scoring in the red zone. He had only four receiving touchdowns last season. Look for that to at least double. Anderson thrived as a possession receiver last season. Some of his production is likely to go to rookie wideout Terrace Marshall Jr. and running back Christian McCaffrey. -- David Newton
New Orleans Saints
Do you expect Marquez Callaway to dominate the target share?
Yes, I expect Callaway to be the Saints' top target -- especially until fellow WR Tre'Quan Smith is fully healed from a nagging hamstring injury that sidelined him all summer and has landed him on the IR to begin the season. Smith was originally expected to be New Orleans' No. 1 receiver while Michael Thomas was out, so he could be a factor again once healthy. But Callaway's emergence as New Orleans' WR1 this summer was no fluke. He stepped up consistently throughout every practice session, just as he did in both preseason games. -- Mike Triplett
Tampa Bay Buccaneers
Is Mike Evans set to be the WR3 in terms of target share this season?
No. The Bucs' coaching staff was absolutely thrilled with the training camp Evans had, with offensive coordinator Byron Leftwich calling him "lights out" and wide receivers coach Kevin Garver saying, "He came into camp the best I've seen him." Evans also said, "This is the best shape I've ever been in." Thursday night's three-catch performance was a combination of Tampa Bay having only so many mouths to feed -- Chris Godwin and Antonio Brown both eclipsed 100 receiving yards -- and Evans being shadowed by Trevon Diggs, who played a terrific game. Should Evans have played better? Absolutely. But it's no reason to hit the panic button. He'll get more than his share. -- Jenna Laine
NFC WEST
Arizona Cardinals
What sort of day one role do you expect for Rondale Moore?
He'll be eased into the receiver rotation in terms of targets, but will see the field early and often Sunday against the Titans. Don't be surprised if he gets a pass and a run early in the first quarter to get his legs under him. Coach Kliff Kingsbury will use him to stretch the defense as well as on plays like jet sweeps. His speed will, undoubtedly, be utilized. -- Josh Weinfuss
Los Angeles Rams
Who will Matthew Stafford target most in his team debut?
That's a tough call between receivers Robert Woods and Cooper Kupp, both of whom Stafford built chemistry with over the offseason and into training camp. Woods' and Kupp's versatility has allowed them to be go-to targets for Stafford anywhere on the field and he is expected to look to both of them often when the Rams open against the Bears. -- Lindsey Thiry
San Francisco 49ers
What does the Raheem Mostert/Trey Sermon touch split look like?
There's little reason to believe the 49ers will stray from the "hot hand" approach they've taken under coach Kyle Shanahan. Which is to say that they'll give Mostert and Sermon (and possibly Elijah Mitchell) opportunities, and whoever seems to be rolling will get the most work. That said, Mostert looked really good in the preseason and camp and Shanahan has said he wants to see what Mostert could do if healthy and able to stay on the field over the course of the season. If things go according to plan and everyone stays healthy, Mostert should be in the 17- to 20-touch range with Sermon probably closer to 9 to 12. -- Nick Wagoner
Seattle Seahawks
Will a third pass-catcher prove productive, and if so who?
Tight end Gerald Everett seems like the most likely candidate, at least for now. Rookie Dee Eskridge might still begin the season as Seattle's third receiver behind Tyler Lockett and DK Metcalf, which is what the Seahawks envisioned when they drafted him in the second round. But all the time he missed because of his toe injury added to an already challenging learning curve. Everett, on the other hand, has had no catching up to do in Shane Waldron's new offense, which is similar to the one he played in while both were with the Rams. -- Brady Henderson